Leptin Concentrations in Non-Obese and Obese Non-Diabetes Nigerian-Africans.

Obiageli Uzoamaka Agbogu-Ike Dimie OgoinaGeoffrey Chukwubuike Onyemelukwe

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)

Plasma leptin concentrations, fasting insulin and insulin resistance are higher in obese and pre-obese than normal controls, with females showing higher leptin concentrations than males. Leptin is independently related to BMI, BFP, WC, female sex and generalized/central obesity in Nigerian-Africans especially males. It showed sex-specific relations to age, fasting insulin and HOMA-IR.

Keyphrases

type diabetes
insulin resistance
adipose tissue
metabolic syndrome
weight loss
glycemic control
blood glucose
high fat diet
obese patients
polycystic ovary syndrome
high fat diet induced
bariatric surgery
cardiovascular disease
skeletal muscle
weight gain