Innovative Nanoscale Drug Delivery Strategies for Breast Carcinoma: A Comprehensive Exploration.
Jaishree SKousalya SelvarajPrakash SVineesh DPublished in: Current drug metabolism (2024)
Breast cancer (BC) is one of the major causes of poor health in women and the most devastating disease after lung cancer. The term "cancer" refers to a collection of problems resulting from abnormal cell proliferation, particularly cells that can spread to other parts of the body. Surgery, followed by chemotherapy or radiotherapy, is now accepted for BC-related cancers. However, chemotherapy and radiotherapy are rarely effective in the treatment of BC due to the adverse effects of these treatments on healthy tissues and organs. Consequently, the use of NPs in targeted Drug Delivery Systems (DDSs) has emerged as a promising strategy for BC treatment. This review provides a summary of recent clinical investigations of nanoparticle-mediated DDS that offer a novel therapeutic strategy commonly used for the treatment of breast cancer.
Keyphrases
- cell proliferation
- drug delivery
- locally advanced
- public health
- gene expression
- healthcare
- early stage
- radiation therapy
- squamous cell carcinoma
- mental health
- type diabetes
- metabolic syndrome
- emergency department
- acute coronary syndrome
- young adults
- replacement therapy
- oxidative stress
- gestational age
- lymph node metastasis
- cell cycle arrest
- breast cancer risk
- papillary thyroid
- pregnancy outcomes