Regulation of the hypoxic tumor environment in hepatocellular carcinoma using RNA interference.

Published in: Cancer cell international (2017)

Therefore, regulation of HIFs and IL-8 controlled the tumor microenvironment in terms of tumor angiogenesis and apoptosis. The review summarizes the results of regulation of the hypoxic tumor environment.

Keyphrases

cell death
endothelial cells
endoplasmic reticulum stress
vascular endothelial growth factor
signaling pathway
pi k akt
nucleic acid