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Pharmacogenetic role of dopamine transporter (SLC6A3) variation on response to disulfiram treatment for cocaine addiction.

June P KampangkaewCatherine J SpellicyEllen M NielsenMark J HardingAn YeSara C HamonThomas R KostenDavid A Nielsen
Published in: The American journal on addictions (2019)
We found that patients with genetically higher DAT levels had better treatment outcomes with disulfiram pharmacotherapy of cocaine dependence than those with lower DAT levels. (Am J Addict 2019;28:311-317).
Keyphrases
  • prefrontal cortex
  • uric acid