Investigation of Fibroblast Growth Factor Peptide Antagonist on Mouse Model Breast Tumor through ERK/MAPK and PI3K/AKT Signaling Pathways.

Shahrzad GhadirianAlireza TabibzadehHamid RezvaniMehrzad Jafarzadeh

Published in: Asian Pacific journal of cancer prevention : APJCP (2024)

The peptide injection was effective in mice model. Findings showed that in the two signal transduction pathways, the p-AKT and p-ERK levels were significantly different from the negative control group.

Keyphrases

pi k akt
signaling pathway
mouse model
cell proliferation
cell cycle arrest
induced apoptosis
epithelial mesenchymal transition
high fat diet induced
type diabetes
metabolic syndrome
cell death
insulin resistance
wild type