A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+-activated Cl- current when transfected into HEK293.

Casilda V MuraRicardo DelgadoMaría Graciela DelgadoDiego RestrepoJuan Bacigalupo

Published in: BMC neuroscience (2017)

These findings suggests that a CLCA isoform, namely CLCA4L, expressed in OSN cilia, might have a regulatory function over the ANO2-dependent Ca2+-activated Cl- channel involved in odor transduction.

Keyphrases

transcription factor
protein kinase
spinal cord
amino acid
protein protein