Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial.
Michael T BrennanLars Siim MadsenDeborah P SaundersJoel J NapenasChristine McCrearyRicheal Ni RiordainAnne Marie Lynge PedersenStefano FedeleRichard J CookRafik AbdelsayedMaria T LlopizVidya SankarKevin RyanDonna A CultonYousra AkhlefFausto CastilloInti FernandezSabine JurgeAlexander R KerrChad McDuffieTim McGawAlan MighellThomas P SollecitoThomas SchlieveMarco CarrozzoAthena PapasThomas BengtssonIbtisam Al-HashimiLaurie BurkeNancy W BurkhartShauna CulshawBhavik DesaiJens HansenPia JensenTorkil MennéParas B PatelMartin ThornhillNathaniel TreisterThomas RuzickaPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2022)
-CLO patches were superior to placebo demonstrating statistically significant, clinically relevant efficacy in objective and subjective improvement and, with a favorable safety profile.