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Pharmacokinetic study of high-dose oral rifampicin in critically Ill patients with multidrug-resistant Acinetobacter baumannii infection.

Hossein Karballaei-MirzahosseiniRomina Kaveh-AhangaranBita ShahramiMohammad Reza RouiniAtabak NajafiArezoo AhmadiSima SadraiAmirmahdi MojtahedzadehFarhad NajmeddinMojtaba Mojtahedzadeh
Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2022)
In critically ill patients with MDR-AB infections, neither fasting nor non-fasting administrations of high-dose oral RIF achieve the therapeutic aims. More research is needed in larger populations and with measuring the amount of protein-unbound RIF levels.
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