Maternal obesity accelerates rat offspring metabolic ageing in a sex-dependent manner.

Guadalupe L Rodríguez-GonzálezLuis Antonio Reyes-CastroClaudia J BautistaAzucena A BeltránCarlos A IbáñezClaudia C VegaConsuelo Lomas-SoriaDiana C Castro-RodríguezAna L Elías-LópezPeter W Nathanielsz Elena Zambrano

Published in: The Journal of physiology (2019)

exposure to the developmental challenge of MO accelerates progeny ageing metabolic and endocrine profiles in a sex specific manner, providing evidence for programming-ageing interactions.

Keyphrases

insulin resistance
metabolic syndrome
type diabetes
high fat diet
oxidative stress
weight gain
birth weight
high fat diet induced
pregnancy outcomes
adipose tissue
body mass index
skeletal muscle
gestational age