Chronic but not acute nicotine treatment ameliorates acute inflammation-induced working memory impairment by increasing CRTC1 and HCN2 in adult male mice.

Xiaona WangQian WangMin SongYihui WangXianzhi ShenYanyun SunChun GuoPanpan GengChaolin MaXin-Chun Jin

Published in: CNS neuroscience & therapeutics (2024)

In summary, in this study, we show that chronic nicotine treatment ameliorates acute inflammation-induced working memory deficiency by increasing CRTC1 and HCN2 in adult male mice.

Keyphrases

working memory
drug induced
liver failure
respiratory failure
transcranial direct current stimulation
oxidative stress
attention deficit hyperactivity disorder
high glucose
aortic dissection
mouse model
smoking cessation
endothelial cells
mechanical ventilation