Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis.
Ming G ChaiQuyen TuMenino O CottaMichelle J BauerRoss BalchCharles OkaforTracy ComansPeter KrugerJason MeyerKiran ShekarKara BradyCheryl FourieNatalie SharpLuminita VladDavid WhileyJacobus P J UngererBrett C McwhinneyAndras FarkasDavid L PatersonJulia E ClarkKrispin HajkowiczSainath RamanSeweryn BialasiewiczJeffrey LipmanBrian M FordePatrick N A HarrisLuregn J SchlapbachLachlan CoinJason A RobertsAdam David IrwinPublished in: Intensive care medicine (2024)
Dosing software may reduce the time to achieve target antibiotic exposures. It should be evaluated further in trials to establish its impact on clinical outcomes.