Steroid treatment in the management of destructive thyrotoxicosis induced by PD1 blockade.
Alessandro BrancatellaLaura PierottiNicola ViolaIsabella LupiLucia MontanelliChiara CremoliniPaolo PiaggiAntonio ChellaAndrea AntonuzzoDaniele SgròLucia AntonangeliChiara SardellaSandra BrogioniClaudio MarcocciFerruccio SantiniFrancesco LatrofaPublished in: European thyroid journal (2022)
Our preliminary data suggest that in patients with a poor performance status experiencing a severe destructive thyrotoxicosis induced by PD-1 blockade, a short period of administration of oral prednisone is effective in obtaining a quick reduction of the levels of thyroid hormones.