Upregulated IL-10 induced by E2F2-miR-17-5p circuitry in extrafollicular effector B cells contributes to autoantibody production in systemic lupus erythematosus.
Lingxiao XuLei WangYumeng ShiYun DengJim C OatesDiane L KamenGary S GilkesonFang WangMiaojia ZhangWenfeng TanBetty P TsaoPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2021)
IL10 promotes extrafollicular autoimmune responses in active SLE patients, which might be dampened by targeting the E2F2-miR-17-5p circuitry.