Effect of High-Fat Meal on the Pharmacokinetics and Safety of Valsartan/Amlodipine Fixed Dose Combination Tablets in Healthy Subjects.
Haojing SongBo QiuXue SunCaihui GuoYiting HuWanjun BaiZhanjun DongPublished in: Drug design, development and therapy (2024)
The result indicated that the high-fat meal had a significant effect on the pharmacokinetics of valsartan, but no effect on amlodipine. All treatments were safe and well tolerated in healthy subjects under fed and fasted conditions.
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