Perfusion Imaging and Clinical Outcome in Acute Minor Stroke With Large Vessel Occlusion.
Pierre SenersCaroline ArquizanLouis FontaineWagih Ben HassenMirjam Rachel HeldnerDavide StramboSimon NagelEmmanuel CarreraLaura MechtouffMargy E McCullough-HicksMahmoud H MohammadenJean-Philippe CottierHilde HénonAndreea AignatoaieNadia LaksiriJérémie PapassinLudovic LucasPierre GarnierAude Triquenot BaganGioia MioneSteven David HajduVincent CostalatArne PotreckOlivier DetanteFabrice BonnevilleYves BerthezeneSerge BracardIgor Paul SibonNicolas BricoutClaire BoutetPasquale MordasiniPatrik MichelCatherine OppenheimJean Marc OlivotRaul Gomes NogueiraGregory W AlbersJean Claude BaronGuillaume Turcnull nullPublished in: Stroke (2022)
In our population of large vessel occlusion-related minor stroke patients, bridging therapy was associated with lower rates of good outcome as compared with IVT alone. However, mismatch volume was a strong modifier of the effect of bridging therapy over IVT alone, notably with worse outcome with bridging therapy in patients with mismatch volume ≤40 mL. Randomized trials should consider adding perfusion imaging for patient selection.