NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients.

Salah ArefRasha RizkMohamed El AgderWafaa FakhryMaha El ZafaranyMohamed Sabry

Published in: Asian Pacific journal of cancer prevention : APJCP (2020)

Our data indicate that NOTCH-1 gene mutations were detected in 12% of AML patients. These mutations displayed bad clinical outcome on AML patients. Therapeutic targeting of NOTCH-1 could be a potentially effective approach to combat master oncogenic drivers in AML.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
acute myeloid leukemia
peritoneal dialysis
cell proliferation
machine learning
drug delivery
deep learning
artificial intelligence
patient reported