Development and validation of genome-wide polygenic risk scores for predicting breast cancer incidence in Japanese females: a population-based case-cohort study.

Hiroyuki OhbeTsuyoshi Hachiya Taiki YamajiShiori NakanoYoshihisa MiyamotoYoichi SutohYayoi Otsuka-YamasakiAtsushi ShimizuHideo YasunagaNorie SawadaManami InoueShoichiro TsuganeMotoki Iwasakinull null

Published in: Breast cancer research and treatment (2022)

This study developed a breast cancer PRS for Japanese females and demonstrated the usefulness of the PRS for breast cancer risk stratification.

Keyphrases

genome wide
dna methylation
risk factors
breast cancer risk
gene expression
young adults
copy number