Assessment of retinal neurodegeneration with spectral-domain optical coherence tomography: a systematic review and meta-analysis.
Ziqi TangMing Yan ChanWai Yin LeungHo Yeung WongChing Man NgVictor T T ChanRaymond WongJerry LokSimon SzetoJason C K ChanClement Chee Yung ThamTien Y WongCarol Y CheungPublished in: Eye (London, England) (2020)
Thinning of retinal neuronal and axonal layers at macula as measured by SD-OCT are presented in eyes with NDR, supporting DRN may be the early pathogenesis in the DM patients without the presence of clinical signs of DR. In the future, these SD-OCT measures may be used as surrogates of DRN to stratify DM patients with a high risk of DR, and may be used as a therapeutic target if neuroprotection treatment for DR is available.
Keyphrases
- optical coherence tomography
- diabetic retinopathy
- optic nerve
- end stage renal disease
- editorial comment
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- cerebral ischemia
- type diabetes
- metabolic syndrome
- current status
- computed tomography
- subarachnoid hemorrhage
- solar cells