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Importance of cerebrospinal fluid storage conditions for the Alzheimer's disease diagnostics on an automated platform.

Rosa FerrerNuole ZhuJavier ArranzInmaculada PorcelShaimaa El BounasriOriol SánchezSoraya TorresJosep JulveAlberto LleóFrancisco Blanco-VacaDaniel AlcoleaMireia Tondo
Published in: Clinical chemistry and laboratory medicine (2022)
Cutoffs calculated in samples stored at -80 °C can be safely used in samples stored at -20 °C for 15-16 days or up to two days at RT and subsequent freezing at -80 °C. For samples stored at 4 °C, cutoffs would require applying a correction factor, allowing to work with the certainty of reaching the same clinical diagnosis.
Keyphrases
  • room temperature
  • cerebrospinal fluid
  • cognitive decline