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Evaluation of [ 18 F]F-DPA PET for Detecting Microglial Activation in the Spinal Cord of a Rat Model of Neuropathic Pain.

Saeka ShimochiThomas KellerElla KujalaJoonas KhabbalJohan RajanderEliisa LöyttyniemiOlof SolinPirjo NuutilaShigehiko KanayaEmrah YatkinTove J GrönroosHidehiro Iida
Published in: Molecular imaging and biology (2022)
F]F-DPA PET did not allow for visualization of tracer accumulation even using a high-spatial-resolution PET scanner. The main reason for this result was due to insufficient SUVs in the spinal cord region as compared with the background noise, in addition to a spillover from the vertebral body.
Keyphrases
  • neuropathic pain
  • spinal cord
  • positron emission tomography
  • spinal cord injury
  • pet imaging
  • pet ct
  • computed tomography
  • bone mineral density
  • single molecule
  • lipopolysaccharide induced
  • body composition