Evaluation of [ 18 F]F-DPA PET for Detecting Microglial Activation in the Spinal Cord of a Rat Model of Neuropathic Pain.

Saeka ShimochiThomas KellerElla KujalaJoonas KhabbalJohan RajanderEliisa LöyttyniemiOlof SolinPirjo NuutilaShigehiko KanayaEmrah YatkinTove J GrönroosHidehiro Iida

Published in: Molecular imaging and biology (2022)

F]F-DPA PET did not allow for visualization of tracer accumulation even using a high-spatial-resolution PET scanner. The main reason for this result was due to insufficient SUVs in the spinal cord region as compared with the background noise, in addition to a spillover from the vertebral body.

Keyphrases

neuropathic pain
spinal cord
positron emission tomography
spinal cord injury
pet imaging
pet ct
computed tomography
bone mineral density
single molecule
lipopolysaccharide induced
body composition