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Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone.

Sanne Ten HoornDirkje W SommeijerFaye ElliottDavid FisherTim R de BackAnne TrinhLianne KoensTim MaughanJenny F SeligmannMatthew T SeymourPhil QuirkeRichard AdamsSusan D RichmanCornelis J A PuntLouis Vermeulen
Published in: British journal of cancer (2021)
The subtype-specific efficacy of anti-EGFR therapy is dependent on the chemotherapy backbone. This may provide the possibility of subtype-specific treatment strategies for a more optimal use of anti-EGFR therapy.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • locally advanced
  • bone marrow
  • rectal cancer
  • replacement therapy