Insights into the effects of Friedreich ataxia on the left ventricle using T1 mapping and late gadolinium enhancement.
Roger E PeverillKimberly Y LinMark A FogelMichael M H CheungW Stuart MoirLouise A CorbenGlenn CahoonMartin B DelatyckiPublished in: PloS one (2024)
An association between diffuse interstitial LV myocardial fibrosis and genetic severity in FRDA was present independently of FRDA-related LV structural changes. Localised replacement fibrosis was found in a minority of subjects with FRDA and was not associated with LV structural change or FRDA genetic severity in subjects with a normal LVEF.