Dysbiotic human oral microbiota alters systemic metabolism via modulation of gut microbiota in germ-free mice.

Kyoko YamazakiEiji MiyauchiTamotsu KatoKeisuke SatoWataru SudaTakahiro TsuzunoMiki Yamada-HaraNobuo SasakiHiroshi OhnoKazuhisa Yamazaki

Published in: Journal of oral microbiology (2022)

The multi-omics approach used in this study revealed that periodontitis-associated oral microbiota is associated with the induction of disease phenotype when they colonized the gut of germ-free mice.

Keyphrases

high fat diet induced
endothelial cells
single cell
insulin resistance
type diabetes
induced pluripotent stem cells
metabolic syndrome