A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies.
Joanna OsmanskaKatriona BrooksbankKieran F DochertyStacy RobertsonKirsty WetherallAlexander McConnachieJerry HuRoy S GardnerAndrew L ClarkIain B SquirePaul R KalraPardeep S JhundPieter MuntendamJohn Joseph Valentine McMurrayMark Colquhoun PetrieRoss T CampbellPublished in: European heart journal. Cardiovascular pharmacotherapy (2023)
The novel preparation of SC furosemide had similar bioavailability to IV furosemide. Administration via a patch pump was feasible and well tolerated.
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