Elevated levels of C3, C4, and CH50 of the complement system in ICU and non-ICU patients with COVID-19.

Ahmad Bagherimoghaddam Houshang Rafat Panah Hassan Mansouritorghabeh

Published in: Health science reports (2022)

These results indicate that the innate immune system was activated in both ICU and non-ICU patients in response to SARS-CoV-2 infection. Further studies with a larger number of COVID-19 patients and additional testing of complement components (C3a and C5a) may reveal the role of COVID-19 infection in the activation of the complement system.

Keyphrases

intensive care unit
mechanical ventilation
innate immune
end stage renal disease
ejection fraction
newly diagnosed
sars cov
prognostic factors
peritoneal dialysis
single cell
dna methylation
case control