Metabolomic profile of cerebrospinal fluid from patients with diffuse gliomas.
Nora MöhnHarold F HounchonouSandra NayPhilipp SchwenkenbecherLea Grote-LeviFadi Al-TarawniMajid EsmailezadehSven SchuchardtKerstin SchwabeHerbert HildebrandtHauke ThieslerFriedrich FeuerhakeChristian HartmannThomas SkripuletzJoachim K KraussPublished in: Journal of neurology (2024)
CSF-metabolome profiling, unlike blood profiling, shows promise as a diagnostic tool for glioma patients with the potential to assign molecular subtypes. The next step will involve a larger multicenter study to validate these findings, with the ultimate objective of integrating CSF metabolomics analysis into clinical practice.