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Metabolomic profile of cerebrospinal fluid from patients with diffuse gliomas.

Nora MöhnHarold F HounchonouSandra NayPhilipp SchwenkenbecherLea Grote-LeviFadi Al-TarawniMajid EsmailezadehSven SchuchardtKerstin SchwabeHerbert HildebrandtHauke ThieslerFriedrich FeuerhakeChristian HartmannThomas SkripuletzJoachim K Krauss
Published in: Journal of neurology (2024)
CSF-metabolome profiling, unlike blood profiling, shows promise as a diagnostic tool for glioma patients with the potential to assign molecular subtypes. The next step will involve a larger multicenter study to validate these findings, with the ultimate objective of integrating CSF metabolomics analysis into clinical practice.
Keyphrases
  • cerebrospinal fluid
  • clinical practice
  • single cell
  • high grade
  • mass spectrometry
  • low grade
  • big data
  • single molecule
  • machine learning
  • risk assessment
  • data analysis