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A finite element model to predict the consequences of endolymphatic hydrops in the basilar membrane.

Bruno AreiasMarco P L ParenteFernanda GentilCristina CaroçaJoão PaçoRenato M Natal Jorge
Published in: International journal for numerical methods in biomedical engineering (2021)
Ménière's disease is an inner ear disorder, associated with episodes of vertigo, fluctuant hearing loss, tinnitus, and aural fullness. Ménière's disease is associated with endolymphatic hydrops. Clinical evidences show that this disease is often incapacitating, negatively affecting the patients' everyday life. The pathogenesis of Ménière's disease is still not fully understood and remains unclear. Previous numerical studies available in the literature related with endolymphatic hydrops, are very scarce. The present work applies the finite element method to investigate the consequences of endolymphatic hydrops in the normal hearing, associated with the Ménière's disease. The obtained results for the steady state dynamics analysis are in accordance with clinical evidences. The results show that the basilar membrane is not affected in the same intensity along its length and that the lower frequencies are more affected by the endolymphatic hydrops. From a clinical point of view, this work shows the relationship between the increasing of the endolymphatic pressure and the development of hearing loss.
Keyphrases
  • hearing loss
  • finite element
  • systematic review
  • end stage renal disease
  • chronic kidney disease
  • ejection fraction
  • prognostic factors
  • high intensity
  • peritoneal dialysis