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Treatment induced clearance of hepatitis E viruses by interferon-lambda in liver-humanized mice.

Gulce SariClaudia E MuldersJingting ZhuGertine W van OordZongdi FengJolanda J C Kreeft-VoermansAndre BoonstraThomas Vanwolleghem
Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)
PegIFNλ is well tolerated in mice and leads to clearance of a persistent HEV infection in liver-humanized mice.
Keyphrases
  • high fat diet induced
  • dendritic cells
  • insulin resistance
  • type diabetes
  • diabetic rats
  • oxidative stress
  • immune response
  • adipose tissue
  • metabolic syndrome
  • combination therapy
  • genetic diversity