Assessing the activity of nonsense-mediated mRNA decay in lung cancer.
Meng WangPeiwei ZhangYufei ZhuXiangyin KongZhenguo ZhangLandian HuPublished in: BMC medical genomics (2017)
In sum, NMD activity varies among lung cancerous samples, which forecasts varying efficacies of NMD-inhibition based therapy. The developed metrics can be further used in other cancer types to assess NMD activity.