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ADHD and depression: investigating a causal explanation.

Lucy RiglinBeate LeppertChristina DardaniAjay K ThaparFrances RiceMichael C O'DonovanGeorge Davey SmithEvie StergiakouliKate TillingAnita Thapar
Published in: Psychological medicine (2020)
Our findings suggest that ADHD increases the risk of depression later in life and are consistent with a causal effect of ADHD genetic liability on subsequent major depression. However, findings were different for more broadly defined depression.
Keyphrases
  • attention deficit hyperactivity disorder
  • autism spectrum disorder
  • depressive symptoms
  • working memory
  • sleep quality
  • genome wide
  • gene expression
  • physical activity
  • copy number