Abnormal expressions of ADAMTS-1, ADAMTS-9 and progesterone receptors are associated with lower oocyte maturation in women with polycystic ovary syndrome.

Sepide GohariTabanIraj AmiriSara Soleimani AslMassoud SaidijamMahnaz YavangiElham KhanlarzadehNooshin MohammadpourNooshin ShababTayebe Artimani

Published in: Archives of gynecology and obstetrics (2018)

The results of the present study indicated that ADAMTS-1 and ADAMTS-9 as well as PRs are downregulated in the human CCs in PCOS patients, which could be associated with impaired oocyte maturation and may result in a lower oocyte recovery and oocyte maturity rates, as well as lower fertilization rate.

Keyphrases

polycystic ovary syndrome
end stage renal disease
endothelial cells
chronic kidney disease
newly diagnosed
ejection fraction
prognostic factors
patient reported outcomes
estrogen receptor
patient reported