Significant compartment-specific impact of different RNA extraction methods and PCR assays on the sensitivity of hepatitis E virus detection.
Patrick BehrendtBirgit BremerDaniel TodtEike SteinmannMichael Peter MannsMarkus CornbergHeiner WedemeyerBenjamin MaasoumyPublished in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Different methods for RNA extraction and quantification have a significant, compartment-specific impact on the sensitivity of HEV detection. Knowledge about the favourable combinations of extraction and quantification has important implications for diagnosis and patients receiving antiviral therapy.