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Natural product pharmacology: the British Journal of Pharmacology perspective.

Shunyao WangAngelo A IzzoAndreas PapapetropoulosStephen P H AlexanderMiriam M Cortese-KrottDave A KendallKirill A MartemyanovClaudio MauroReynold A PanettieriHemal H PatelRainer SchulzBarbara StefanskaGary J StephensMauro Martins TexeiraNathalie VergnollePéter Ferdinandy
Published in: British journal of pharmacology (2024)
Natural products (NPs) have long been used as a rich source of bioactive compounds for drug development. Recent technological advancements have revitalised natural products research as evidenced by increased publications in this field. In this editorial review, we highlight key points from the 2020 British Journal of Pharmacology (BJP) practical guide, which outlines standards for natural products research reports, and provide papers published in BJP between years 2020 to 2023 that demonstrate adherence to these guidelines. Looking ahead, we discuss the potential of chemical proteomics approaches to elucidate natural products mechanisms of action and identify therapeutic targets for future research. By fostering innovation, we aim to advance natural products research and contribute to the development of novel therapeutics that will have a significant impact on healthcare.
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