An Antiviral Drug-Peramivir: Degradation and Identification of Impurities and the Endorsement of HPLC-MS Method.

An HPLC method was developed and put to the test in order to analyse the behavior of the impurities of peramivir as they degraded when subjected to the stress conditions suggested by the ICH.The compound was discovered to be stable under peroxide and photo conditions but degradable towards the acid, base and thermal. The method developed was extremely precise, linear, accurate, robust, and rugged.As a result, this technology has the potential to be used in the medication production process for regular impurity analysis as well as for the stability analysis of peramivir.