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Outcome of patients with chronic myeloid leukemia in lymphoid blastic phase and Philadelphia chromosome-positive acute lymphoblastic leukemia treated with hyper-CVAD and dasatinib.

Kiyomi MoritaHagop M KantarjianKoiji SasakiGhayas C IssaNitin JainMarina KonoplevaNicholas James ShortKoichi TakahashiCourtney D D DiNardoTapan Mahendra KadiaGuillermo Garcia ManeroNaval G DaverGuillermo Montalban BravoJorge E CortesFarhad RavandiElias J Jabbour
Published in: Cancer (2021)
The outcome of CML-LBP has improved with hyper-CVAD plus dasatinib therapy with survival comparable to that of Ph-positive ALL. Further improvement may be achieved with the use of novel TKIs and targeted agents.
Keyphrases
  • chronic myeloid leukemia
  • acute lymphoblastic leukemia
  • allogeneic hematopoietic stem cell transplantation
  • cancer therapy
  • stem cells
  • copy number
  • gene expression
  • bone marrow
  • drug delivery