A Comparison of the Blood Glucose, Growth Hormone, and Cortisol Responses to Two Doses of Insulin (0.15 U/kg vs. 0.10 U/kg) in the Insulin Tolerance Test: A Single-Centre Audit of 174 Cases.
Phillip YeohAndrew A DwyerElla AnghelPierre M BoulouxBernard KhooShern ChewFlorian WernigPaul V CarrollSimon J B AylwinStephanie E BaldewegWilliam DrakeJeannie ToddLindiwe MangenaAshley B GrossmanPublished in: International journal of endocrinology (2022)
Our results suggest that the low-dose ITT produces comparable glucose, cortisol, and GH responses to the higher dose. Given the risks associated with hypoglycaemia, the low dose appears to be preferable to the standard dose ITT in most circumstances.