Type 2 Poliovirus Detection after Global Withdrawal of Trivalent Oral Vaccine.
Isobel M BlakeMargarita Pons-SalortNatalie A MolodeckyOusmane M DiopPaul ChenowethAnanda S BandyopadhyayMichel ZaffranRoland W SutterNicholas C GrasslyPublished in: The New England journal of medicine (2018)
High population immunity has facilitated the decline in the prevalence of Sabin-2 poliovirus after OPV2 withdrawal and restricted the circulation of VDPV2 to areas known to be at high risk for transmission. The prevention of VDPV2 outbreaks in these known areas before the accumulation of substantial cohorts of children susceptible to type 2 poliovirus remains a high priority. (Funded by the Bill and Melinda Gates Foundation and the World Health Organization.).