Faecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis.
Henriette KreimeyerCarlos G GonzalezMarcos F FondevilaCynthia L HsuPhillipp HartmannXinlian ZhangPeter StärkelFrancisco BosquesElizabeth C VernaJuan G AbraldesRobert S BrownVictor VargasJose AltamiranoJuan CaballeríaDebbie Lindsay ShawcrossAlexandre LouvetMichael R LuceyPhilippe MathurinGuadalupe Garcia-TsaoRamón BatallerAlcHepNet InvestigatorsDavid J GonzalezBernd SchnablPublished in: Gut (2024)
We found an increased abundance of faecal proteins linked to neutrophil degranulation in patients with AH, which is predictive of short-term survival and could serve as a prognostic non-invasive marker.