Overview of Small Molecules as Fluorescent Probes of Mycobacterium tuberculosis .
Konstantina StavropoulouIoannis P PapanastasiouPublished in: ACS omega (2024)
Tuberculosis (TB) remains one of the leading infectious causes of death worldwide. Detecting and precisely quantifying viable Mycobacterium tuberculosis ( M. tuberculosis ) is crucial for comprehending mycobacterial pathogenicity; the progression and outcomes of tuberculosis; and the action, efficacy, and resistance of drugs. Fluorescent probes have emerged as indispensable tools for studying the intricate structure and dynamic interactions of M. tuberculosis with its host environment. This minireview underscores the significance of small molecules as fluorescent probes in advancing our understanding of mycobacterial biology and highlights their potential for guiding the development of novel therapeutic interventions against tuberculosis.
Keyphrases
- mycobacterium tuberculosis
- living cells
- pulmonary tuberculosis
- small molecule
- quantum dots
- fluorescent probe
- single molecule
- fluorescence imaging
- physical activity
- escherichia coli
- type diabetes
- hiv aids
- hepatitis c virus
- risk assessment
- cystic fibrosis
- climate change
- weight loss
- adipose tissue
- label free
- human health
- nucleic acid