Peripheral Latanoprost Administration Lowers Intraocular Pressure in the Wistar Rat.
Maciej ŚwiątkiewiczMarlena Wełniak-KamińskaMichał FiedorowiczAgnieszka KamińskaRobert RejdakPaweł GriebPublished in: Ophthalmology and therapy (2020)
Subcutaneous continuous delivery of latanoprost decreased the IOP in the conscious normotensive Wistar rats in this study. If this effect is confirmed in humans, it may open the possibility of using peripheral systems of drug delivery, which could significantly improve patient compliance.