Feasibility of Using Gluconolactone, Trehalose and Hydroxy-Propyl Gamma Cyclodextrin to Enhance Bendroflumethiazide Dissolution Using Lyophilisation and Physical Mixing Techniques.
Ashraf SalehKenneth McGarryCheng Shu ChawAmal Ali ElkordyPublished in: Pharmaceutics (2018)
the physical mixing and freeze drying processes significantly increased the percentage of drug release with time.