IMPACT OF KRAS MUTATIONS IN CLINICAL FEATURES IN COLORECTAL CANCER.
Renato Morato ZanattoGianni SantosJúnea Caris de OliveiraEduardo Marcucci PracuchoAdauto José Ferreira NunesGaspar de Jesus Lopes FilhoSarhan Sydney SaadPublished in: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery (2020)
The KRAS mutation was identified in almost half of patients. Mutated KRAS group had higher levels of CEA at admission and the mutation at codon 13 was associated with involvement of more than one metastatic site in the course of the disease. Colon disease was associated with the worst overall survival.