bFGF promotes neurological recovery from neonatal hypoxic-ischemic encephalopathy by IL-1β signaling pathway-mediated axon regeneration.

Zheng MaFang WangLu-Lu XueYing-Jie NiuYue HuZhang-Yu SuJin HuangRui-Ze NiuTing-Hua WangYing-Chun BaLiu-Lin XiongXue Bai

Published in: Brain and behavior (2020)

We showed that IL-1β-mediated axon regeneration underlie the mechanism of bFGF for the treatment of HIBD in neonatal rats. Results from this study would provide insights and molecular basis for future therapeutics in treating HIBD.

Keyphrases

combination therapy
stem cells
signaling pathway
small molecule
early onset
pi k akt
epithelial mesenchymal transition
wound healing
current status
oxidative stress
cell proliferation
endoplasmic reticulum stress
optical coherence tomography