Long-term outcomes of mesial temporal laser interstitial thermal therapy for drug-resistant epilepsy and subsequent surgery for seizure recurrence: a multi-centre cohort study.
Brett E YoungermanMatei A BanuFarhan KhanGuy M McKhannCatherine A SchevonJonathan R JagidIahn CajigasChristian B TheodotouAndrew L KoRobert BuckleyJeffrey G OjemannJohn W MillerAdrian W LaxtonDaniel E CoutureGautam S PopliVivek P BuchCasey H HalpernScheherazade LeAshwini D SharanMichael R SperlingAshesh D MehtaDario J EnglotJoseph S NeimatPeter E KonradSameer A ShethElliot G NealFernando L ValeKathryn L HollowayEllen L AirJason M SchwalbPierre-François D'HaeseChengyuan WuPublished in: Journal of neurology, neurosurgery, and psychiatry (2023)
MRgLITT is a viable treatment with durable outcomes for patients with drug-resistant mTLE evaluated at a comprehensive epilepsy centre. Although seizure freedom rates were lower than reported with ATL, this series represents the early experience of each centre and a heterogeneous cohort. ATL remains a safe and effective treatment for well-selected patients who fail MRgLITT.