Rapid antidepressant effects of deep brain stimulation of the pre-frontal cortex in an animal model of treatment-resistant depression.

Mariusz PappPiotr GrucaMagdalena LasonKatarzyna Tota-GlowczykMonika NiemczykEwa LitwaPaul Willner

Published in: Journal of psychopharmacology (Oxford, England) (2018)

These data provide a proof of principle that deep brain stimulation of the prefrontal cortex can be effective in a rat model of resistance to chronic antidepressant treatment, replicating the clinical effect of deep brain stimulation in treatment-resistant depression.

Keyphrases

deep brain stimulation
parkinson disease
prefrontal cortex
obsessive compulsive disorder
major depressive disorder
depressive symptoms
functional connectivity
sleep quality
electronic health record
working memory
big data
combination therapy
quantum dots
smoking cessation
deep learning