Cardiovascular concentration-effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and preclinical studies.

Xin Hui S Chan Palang ChotsiriRebecca A CapelJames PikeBorimas HanboonkunupakarnSue J LeeMaryam HanafiahYan Naung WinMaegan A CremerJean-René KiechelBernhards OgutuWalter R J TaylorRebecca-Ann B BurtonJoel Tarning Nicholas J White

Published in: British journal of clinical pharmacology (2022)

Amodiaquine and desethylamodiaquine have concentration-dependent effects on heart rate, blood pressure, and ventricular repolarization.

Keyphrases

heart rate
blood pressure
heart rate variability
hypertensive patients
left ventricular
cell therapy
case control
stem cells
metabolic syndrome
blood glucose
atrial fibrillation
mesenchymal stem cells
skeletal muscle
insulin resistance
weight loss