Nonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects.

Yonghui HouBingyu ZhouMing NiMin WangLingli DingYing LiYamei LiuWencai ZhangGang LiJiali WangLiangliang Xu

Published in: Stem cell research & therapy (2022)

Taken together, we have found U0126 promoted tenogenesis in TSPCs through activating GDF6, and NBM loaded with U0126 significantly promoted tendon defect healing, which provides a new treatment for tendon injury.

Keyphrases

signaling pathway
drug delivery
anterior cruciate ligament reconstruction
pi k akt