Evinacumab in homozygous familial hypercholesterolaemia: long-term safety and efficacy.
Daniel GaudetSusanne Greber-PlatzerLaurens F ReeskampGabriella IannuzzoRobert S RosensonSamir SahebClaudia StefanuttiErik StroesAlbert WiegmanTraci TurnerShazia AliPoulabi BanerjeeTiera DreweryJennifer McGinnissAlpana WaldronRichard T GeorgeXue-Qiao ZhaoRobert PordyJian ZhaoEric BruckertFrederick J RaalPublished in: European heart journal (2024)
In this large cohort of patients with HoFH, evinacumab was generally well tolerated and markedly decreased LDL-C irrespective of age and sex. Moreover, the efficacy and safety of evinacumab was sustained over the long term.
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