A novel high-risk subpopulation identified by CTSL and ZBTB7B in gastric cancer.

Kaisa CuiSurui YaoBingxin LiuShengbai SunLiang GongQilin LiBojian FeiZhaohui Huang

Published in: British journal of cancer (2022)

We identified a high-risk subpopulation with unique TME features based on expressions of CTSL and ZBTB7B, suggesting a counterbalancing phenotype between immunostimulatory and immunosuppressive mechanisms. This subtyping system could be used to select treatment and management strategies for GC.

Keyphrases

combination therapy
replacement therapy
liquid chromatography