Relationship Between Ascending Thoracic Aortic Diameter and Blood Pressure: A Mendelian Randomization Study.
John DePaoloMichael G LevinCatherine TcheandjieuJames R PriestDipender GillStephen BurgessScott M DamrauerJulio Alonso ChirinosPublished in: Arteriosclerosis, thrombosis, and vascular biology (2023)
BP likely contributes causally to ascending thoracic aortic dilation. Increased AscAoD likely contributes to lower systolic BP and pulse pressure, but not diastolic BP, consistent with the hemodynamic consequences of a reduced aortic diameter.
Keyphrases
- blood pressure
- left ventricular
- aortic dissection
- pulmonary artery
- aortic valve
- hypertensive patients
- spinal cord
- coronary artery
- pulmonary hypertension
- heart rate
- optic nerve
- type diabetes
- blood glucose
- metabolic syndrome
- spinal cord injury
- adipose tissue
- optical coherence tomography
- weight loss
- insulin resistance
- skeletal muscle